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INTEGRIN ALPHA4BETA1
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DeCS
Descriptor
English
:
Integrin alpha4beta1
Descriptor
Spanish
:
Integrina alfa4beta1
Descriptor
Portuguese
:
Integrina alfa4beta1
Tree Number:
D12.776.395.550.200.625.347
D12.776.543.550.200.625.347
D12.776.543.750.705.408.530.500
D12.776.543.750.705.408.850.299
D12.776.543.750.705.877.347
D23.050.301.264.035.850.347
D23.050.301.350.625.347
D23.101.100.110.850.347
Definition
English
:
Integrin alpha4beta1
is a FIBRONECTIN and VCAM-1 receptor present on
LYMPHOCYTES
;
MONOCYTES
;
EOSINOPHILS
; NK CELLS and
thymocytes
. It is involved in both cell-cell and cell-
EXTRACELLULAR MATRIX
adhesion and plays a role in
INFLAMMATION
, hematopoietic cell homing and immune function, and has been implicated in skeletal MYOGENESIS;
NEURAL CREST
migration
and proliferation, lymphocyte maturation and
morphogenesis
of the
PLACENTA
and HEART.
History Note
English
:
2003; use INTEGRIN ALPHA4BETA1 (NM) 1991-2002
Allowable Qualifiers
English
:
AD
administration & dosage
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PH
physiology
RE
radiation effects
TU
therapeutic use
UL
ultrastructure
Record Number:
37448
Unique Identifier:
D039041
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
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